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70 积分 2025-03-14 加入
Rationale for Poly(ADP-ribose) Polymerase (PARP) Inhibitors in Combination Therapy with Camptothecins or Temozolomide Based on PARP Trapping versus Catalytic Inhibition
2个月前
已完结
The USP1 Inhibitor KSQ-4279 Overcomes PARP Inhibitor Resistance in Homologous Recombination–Deficient Tumors
2个月前
已完结
A Peptide-Based PROTAC Degrader of BRCA2 Sensitizes Metastatic Castration-Resistant Prostate Cancer to PARP Inhibition
2个月前
已完结
Emerging roles of PARP-1 driven dual inhibitors in cancer therapy: SAR-guided strategies and synthetic lethality
2个月前
已完结
Synthesis and biological evaluation of piperidyl benzimidazole carboxamide derivatives as potent PARP-1 inhibitors and antitumor agents
5个月前
已关闭
N-Benzyl arylamide derivatives as novel and potent tubulin polymerization inhibitors against gastric cancers: Design, structure–activity relationships and biological evaluations
6个月前
已完结
Versatile, tunable method for NaNO2/HX (Cl or Br)–mediated radical dihalogenation or nitration of olefins
7个月前
已完结
Asymmetric synthesis of (R)-reticuline. A new strategy for the asymmetric synthesis of isoquinolines via enantioselective epoxidation or dihydroxylation
10个月前
已完结
The Asymmetric Total Synthesis of (+)-Reticuline
10个月前
已完结
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