Lv1
2 积分 2022-11-06 加入
Design, synthesis and biological evaluation of indazole derivatives as selective covalent inhibitors of FGFR4 in wild-type and gatekeeper mutants
5小时前
已完结
Discovery of 6-Formylpyridyl Urea Derivatives as Potent Reversible-Covalent Fibroblast Growth Factor Receptor 4 Inhibitors with Improved Anti-Hepatocellular Carcinoma Activity
6小时前
已完结
Discovery of 2,6-Naphthyridine Analogues as Selective FGFR4 Inhibitors for Hepatocellular Carcinoma
6小时前
已完结
First-in-Human Phase I Study of Fisogatinib (BLU-554) Validates Aberrant FGF19 Signaling as a Driver Event in Hepatocellular Carcinoma
6小时前
已完结
Nanozyme‐Reinforced Hydrogel Spray as a Reactive Oxygen Species‐Driven Oxygenator to Accelerate Diabetic Wound Healing
1个月前
已完结
Molybdenum Disulfide-Supported Cuprous Oxide Nanocomposite for Near-Infrared-I Light-Responsive Synergistic Antibacterial Therapy
1个月前
已完结
Discovery of SHP2-D26 as a First, Potent, and Effective PROTAC Degrader of SHP2 Protein
5个月前
已完结
Selective and reversible modification of kinase cysteines with chlorofluoroacetamides
5个月前
已完结
Discovery of a Selective and Orally Bioavailable FGFR2 Degrader for Treating Gastric Cancer
5个月前
已完结
Chemistries of bifunctional PROTAC degraders
5个月前
已完结