Lv3
202 积分 2026-08-10 加入
Development of Orally Bioavailable Peptides Targeting an Intracellular Protein: From a Hit to a Clinical KRAS Inhibitor
11天前
已完结
Derisking Affinity Optimization for Macrocycles and Cyclic Peptides: High-Precision Free Energy Simulations across Five Diverse Targets
11天前
已完结
A Series of Novel, Highly Potent, and Orally Bioavailable Next-Generation Tricyclic Peptide PCSK9 Inhibitors
11天前
已完结
Recapitulating the Binding Affinity of Nrf2 for KEAP1 in a Cyclic Heptapeptide, Guided by NMR, X-ray Crystallography, and Machine Learning
11天前
已完结
Structure‐based design of a T‐cell receptor leads to nearly 100‐fold improvement in binding affinity for pepMHC
11天前
已完结
Structure–Activity Studies in a Family of β-Hairpin Protein Epitope Mimetic Inhibitors of the p53–HDM2 Protein–Protein Interaction
11天前
已完结
Robust Prediction of Relative Binding Energies for Protein–Protein Complex Mutations Using Free Energy Perturbation Calculations
18天前
已完结
Kinetics and Thermodynamics of Reversible Thiol Additions to Mono- and Diactivated Michael Acceptors: Implications for the Design of Drugs That Bind Covalently to Cysteines
19天前
已完结
A chemigenetic endogenous Ras activity biosensor for live-cell pharmacology
26天前
已完结
Breaking the Gender Imbalance: Female Presence in the Computational Chemistry Group at Viva Biotech
1个月前
已完结
Curriculum-Integrated MRI Simulation Across Successive Cohorts: A Quasi-experimental Curriculum-Development Study of Cognitive Load and Instructional Efficiency
6小时前
待审核
Oxygen Vacancy Engineering toward Enhanced Dielectric and Ionic Conductivity Properties in Single Crystal LiNbMoO 6
6小时前
待审核
Static Magnetism and Vibration-Modulated Magnetic Relaxation Mechanism of DySc2N@C80 Single-Molecule Magnets
6小时前
待审核
Psychometric validation of the seven-time dimensions scale: a measure of daily time experience quality for nurses’ mental health
6小时前
已采纳
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