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Conformational Properties of Aromatic Amides Bearing Imidazole Ring and Acid-Induced Trans–Cis Amide Switching
6天前
已完结
“Magic Chloro”: Profound Effects of the Chlorine Atom in Drug Discovery
14天前
已完结
Discovery of an ITK and TRK kinase inhibitor for the potential topical treatment of atopic dermatitis
29天前
已完结
Screening through Lead Optimization of High Affinity, Allosteric Cyclin-Dependent Kinase 2 (CDK2) Inhibitors as Male Contraceptives That Reduce Sperm Counts in Mice
1个月前
已完结
Strategic Design of Triple GLP-1R/GCGR/GIPR Agonists with Varied Receptor Potency: Achieving Comparable Glycemic and Weight Reduction Effects
2个月前
已完结
Comprehensive computational modeling and interactions mechanisms of GIPR homodimerization
2个月前
已关闭
Structure–Activity Relationship Guided Scaffold Hopping Resulted in the Identification of GLPG4970, a Highly Potent Dual SIK2/SIK3 Inhibitor
2个月前
已完结
Helicogenic Amino Acid Increases Passive Permeability and Oral Bioavailability of Macrocycles by Preorganizing γ-Turn
2个月前
已完结
Coibamide Analogue as a Novel-Class Payload for Antibody-Drug Conjugate
2个月前
已完结
Discovery of novel and selective SIK2 inhibitors by the application of AlphaFold structures and generative models
2个月前
已完结
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