Lv5
968 积分 2021-04-09 加入
In vitro and in vivo ADME of heterobifunctional degraders: a tailored approach to optimize DMPK properties of PROTACs©
2天前
已完结
Integrating the Impact of Lipophilicity on Potency and Pharmacokinetic Parameters Enables the Use of Diverse Chemical Space during Small Molecule Drug Optimization
3天前
已完结
Pyrazole Ureas as Low Dose, CNS Penetrant Glucosylceramide Synthase Inhibitors for the Treatment of Parkinson’s Disease
3天前
已完结
Invention of MK-7845, a SARS-CoV-2 3CL Protease Inhibitor Employing a Novel Difluorinated Glutamine Mimic
3天前
已完结
Paclitaxel nano-conjugated to polyhedral oligomeric silsesquioxane (POSS) nanoparticles as a novel water-soluble prodrug
5天前
已关闭
Synthesis and Biological Evaluation of C-13 Amide-Linked Paclitaxel (Taxol) Analogs
10天前
已完结
Discovery and Characterization of RP03707: A Highly Potent and Selective KRASG12D PROTAC
12天前
已完结
A patent review of IDO1 inhibitors for cancer (2023 – present): an update
14天前
已完结
Validation, Key Pharmacophores, and X-ray Cocrystal Structures of Novel Biochemically and Cellularly Active WRN Inhibitors Derived from a DNA-Encoded Library Screen
16天前
已完结
Discovery and Characterization of PVTX-321 as a Potent and Orally Bioavailable Estrogen Receptor Degrader for ER+/HER2– Breast Cancer
25天前
已完结
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