Lv5
868 积分 2021-04-09 加入
Structural and conformational determinants of macrocycle cell permeability
27天前
已完结
A Novel Family of Acid-Cleavable Linker Based on Cyclic Acetal Motifs for the Production of Antibody-Drug Conjugates with High Potency and Selectivity
28天前
已完结
Discovery of PF-06873600, a CDK2/4/6 Inhibitor for the Treatment of Cancer
1个月前
已完结
An allosteric cyclin E-CDK2 site mapped by paralog hopping with covalent probes
1个月前
已完结
Discovery of AZD8421: A Potent CDK2 Inhibitor with Selectivity Against Other CDK Family Members and the Human Kinome
1个月前
已完结
An Adenosine Analogue Library Reveals Insights into Active Sites of Protein Arginine Methyltransferases and Enables the Discovery of a Selective PRMT4 Inhibitor
1个月前
已完结
Tailoring PRMT Inhibition: Shifting PRMT7 Selectivity to PRMT4 through “T-Shape” Strategy and “Linker-Specific” Preferences
1个月前
已完结
Identification and characterization of small compound inhibitors of human FATP2
1个月前
已完结
Chemical inhibition of fatty acid absorption and cellular uptake limits lipotoxic cell death
1个月前
已完结
Improving Cognition in Bipolar Disorder: A Systematic Review of Current Pharmacological and Nutraceutical Approaches
1个月前
已完结
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