Lv7
4540 积分 2021-05-06 加入
Discovery of Tivumecirnon (FLX475), a Potent and Selective CCR4 Antagonist That Inhibits the Migration of Immunosuppressive Regulatory T Cells into the Tumor Microenvironment to Restore Antitumor Immunity
14天前
已完结
Accelerated Discovery of Macrocyclic CDK2 Inhibitor QR-6401 by Generative Models and Structure-Based Drug Design
21天前
已完结
Role of interferon regulatory factor 5 (IRF5) in tumor progression: Prognostic and therapeutic potential
1个月前
已完结
Identification and Biological Evaluation of a Potent and Selective JAK1 Inhibitor for the Treatment of Pulmonary Fibrosis
1个月前
已完结
JAK inhibitor selectivity: new opportunities, better drugs?
1个月前
已完结
The Emerging Safety Profile of JAK Inhibitors in Rheumatic Diseases
1个月前
已完结
The Evolving Landscape of JAK-STAT Inhibition in the Treatment of Immune Mediated Inflammatory Diseases
1个月前
已完结
A First-In-Human Study of ARO-RAGE, A Novel Inhaled RNA-Interference Therapy for Asthma
1个月前
已完结
Nerandomilast, a PDE4B inhibitor, alleviates silica‐induced lung inflammation and fibrosis by inhibition of NLRP3 inflammasome and TGF‐β/Smad signalling
1个月前
已完结
A Novel Interleukin-11 Receptor Antibody, LASN01 Is Well Tolerated and Demonstrates Target Engagement in Phase 1
2个月前
已关闭