Lv75
4380 积分 2021-05-06 加入
Nerandomilast, a PDE4B inhibitor, alleviates silica‐induced lung inflammation and fibrosis by inhibition of NLRP3 inflammasome and TGF‐β/Smad signalling
11天前
已完结
A Novel Interleukin-11 Receptor Antibody, LASN01 Is Well Tolerated and Demonstrates Target Engagement in Phase 1
16天前
已关闭
Interleukin-11 is a therapeutic target in idiopathic pulmonary fibrosis
18天前
已完结
Targeting Multiple KRAS Mutations with High-Affinity Macrocyclic Inhibitors: From Discovery to Preclinical Validation
23天前
已完结
Antibody-Mediated Delivery of BRM/BRG1 Protein Degraders Affords Strong Antitumor Efficacy in Multiple BRM-Dependent Non-Small Cell Lung Cancer Xenograft Models
24天前
已完结
A Small-Molecule Drug Conjugate Targeting FAP Exhibits Potent Activity in Dogs with Spontaneous Tumors
25天前
已完结
Lipid and Carbohydrate Modifications Enhance Potency of Antisense Oligonucleotides Targeting Oncogenic KRAS
1个月前
已完结
Peptidomimetics via modifications of amino acids and peptide bonds
1个月前
已完结
Discovery of Small-Molecule GLP-1 Receptor Agonists with Improved Oral Pharmacokinetics Based on Orforglipron
1个月前
已完结
Necroptosis in Lung Diseases: Mechanism and Therapeutic Prospects
1个月前
已完结