Lv1
30 积分 2026-01-31 加入
Discovery of Highly Potent, Selective, and Liver-Targeted THR-β Agonists for the Treatment of Metabolic Dysfunction-Associated Steatohepatitis
21天前
已完结
Harnessing FBXO31 with terminal amide-functionalized molecules for targeted protein degradation
22天前
已完结
Discovery of Rigid Linker-Based IRAK4 PROTACs with Improved Metabolic Stability for the Treatment of Inflammatory Diseases
26天前
已完结
Mitochondrial control of glycerolipid synthesis by a PEP shuttle
27天前
已完结
Deep-learning-based de novo discovery and design of therapeutics that reverse disease-associated transcriptional phenotypes
28天前
已完结
Comparative study of obeticholic acid and rosuvastatin in high-fat/fructose diet–induced metabolic dysfunction: role of AMPK, PPAR-γ, SREBP-1c, and STAT3 pathways
1个月前
已完结
Peroxisome Proliferator-Activated Receptor α/γ Dual Agonists for the Treatment of Type 2 Diabetes
1个月前
已完结
Fine Tuning of PPAR Ligands for Type 2 Diabetes and Metabolic Syndrome
1个月前
已完结
Feeding induces cholesterol biosynthesis via the mTORC1–USP20–HMGCR axis
1个月前
已完结
Inhibition of ASGR1 decreases lipid levels by promoting cholesterol excretion
1个月前
已完结