Lv1
30 积分 2026-01-31 加入
RIMTAC: A Novel Degrader Design Platform by Indirect VHL-Recruitment via RIPK1
1个月前
已完结
Harnessing FBXO31 with terminal amide-functionalized molecules for targeted protein degradation
2个月前
已完结
Safety considerations for cereblon-recruiting targeted protein degraders
4个月前
已完结
Straightforward access to N-trifluoromethyl amides, carbamates, thiocarbamates and ureas
4个月前
已完结
Discovery of Highly Potent, Selective, and Liver-Targeted THR-β Agonists for the Treatment of Metabolic Dysfunction-Associated Steatohepatitis
5个月前
已完结
Harnessing FBXO31 with terminal amide-functionalized molecules for targeted protein degradation
5个月前
已完结
Discovery of Rigid Linker-Based IRAK4 PROTACs with Improved Metabolic Stability for the Treatment of Inflammatory Diseases
5个月前
已完结
Mitochondrial control of glycerolipid synthesis by a PEP shuttle
5个月前
已完结
Deep-learning-based de novo discovery and design of therapeutics that reverse disease-associated transcriptional phenotypes
5个月前
已完结
Comparative study of obeticholic acid and rosuvastatin in high-fat/fructose diet–induced metabolic dysfunction: role of AMPK, PPAR-γ, SREBP-1c, and STAT3 pathways
5个月前
已完结