Lv51
890 积分 2024-01-24 加入
Utility of Coproporphyrin-I Determination in First-in-Human Study for Early Evaluation of OATP1B Inhibitory Potential Based on Investigation of Ensitrelvir, an Oral SARS-CoV-2 3C-Like Protease Inhibitor
3小时前
求助中
Method development and validation for simultaneous determination of ebastine and its active metabolite carebastine in human plasma by liquid chromatography–tandem mass spectrometry and its application to a clinical pharmacokinetic study in healthy Chinese volunteers
3天前
已完结
Comparison of the Circulating Metabolite Profile of PF-04991532, a Hepatoselective Glucokinase Activator, Across Preclinical Species and Humans: Potential Implications in Metabolites in Safety Testing Assessment
3个月前
已完结
A Radiocalibration Method with Pseudo Internal Standard to Estimate Circulating Metabolite Concentrations
3个月前
已完结
Metabolite Identification in the Preclinical and Clinical Phase of Drug Development
3个月前
已完结
Chemical metabolite synthesis and profiling: Mimicking in vivo biotransformation reactions
3个月前
已完结
Overview of metabolite safety testing from an industry perspective
3个月前
已完结
Overview of metabolite safety testing from an industry perspective
3个月前
已关闭
Pharmacokinetics, mass balance, and metabolism of [14C]SAF-189s, a potent anaplastic lymphoma kinase/c-ROS proto-oncogene 1 inhibitor in humans: Metabolism potentially affected by interaction of cytochrome P450 enzymes and intestinal microbiota
4个月前
已关闭
Nonclinical Absorption, Distribution, Metabolism, Excretion and Biomarkers Properties of a Modified N-Acetylgalactosamine–Conjugated Small Interfering RNA for Hypercholesteremia
4个月前
已关闭
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