Lv6
2180 积分 2022-02-16 加入
PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase
1个月前
已完结
Amino-oxetanes as amide isosteres by an alternative defluorosulfonylative coupling of sulfonyl fluorides
1个月前
已完结
Identification of Potential DCAF1 Inhibitors Through Virtual Screening Based on Molecular Docking and Molecular Dynamics Simulations
4个月前
已完结
Direct deaminative functionalization with N-nitroamines
5个月前
已完结
Discovery of a Novel Series of iso-Indolinone-Based Glutarimides as Highly Efficacious and Selective IKZF2 Molecular Glue Degraders
8个月前
已完结
A Unified Approach to Lactonization/Lactamization by Leveraging Tether-Tunable Distonic Radical Anions
8个月前
已完结
One-Step Regioselective Synthesis of N-1-Substituted Dihydrouracils: A Motif of Growing Popularity in the Targeted Protein Degradation Field
8个月前
已完结
Discovery of TQ-3959 as a Potent and Orally Bioavailable BTK PROTAC Degrader Incorporating a Novel Benzisoxazole-Based CRBN Ligand for the Treatment of B-Cell Malignancies
8个月前
已完结
Discovery and Preclinical Pharmacology of NX-2127, an Orally Bioavailable Degrader of Bruton’s Tyrosine Kinase with Immunomodulatory Activity for the Treatment of Patients with B Cell Malignancies
8个月前
已完结
A Concise and Modular Approach to Generate Novel RORγ Agonists
8个月前
已完结
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