Lv6
2170 积分 2022-02-16 加入
Preclinical pharmacokinetics and metabolism of MAK683, a clinical stage selective oral embryonic ectoderm development (EED) inhibitor for cancer treatment
2个月前
已完结
Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex
2个月前
已完结
PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase
6个月前
已完结
Amino-oxetanes as amide isosteres by an alternative defluorosulfonylative coupling of sulfonyl fluorides
6个月前
已完结
Identification of Potential DCAF1 Inhibitors Through Virtual Screening Based on Molecular Docking and Molecular Dynamics Simulations
9个月前
已完结
Direct deaminative functionalization with N-nitroamines
10个月前
已完结
Discovery of a Novel Series of iso-Indolinone-Based Glutarimides as Highly Efficacious and Selective IKZF2 Molecular Glue Degraders
1年前
已完结
A Unified Approach to Lactonization/Lactamization by Leveraging Tether-Tunable Distonic Radical Anions
1年前
已完结
One-Step Regioselective Synthesis of N-1-Substituted Dihydrouracils: A Motif of Growing Popularity in the Targeted Protein Degradation Field
1年前
已完结
Discovery of TQ-3959 as a Potent and Orally Bioavailable BTK PROTAC Degrader Incorporating a Novel Benzisoxazole-Based CRBN Ligand for the Treatment of B-Cell Malignancies
1年前
已完结
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