Lv5
1048 积分 2022-08-03 加入
Discovery and Development of AMG 333: A TRPM8 Antagonist for Migraine
6天前
已完结
In Vitro and In Vivo Pharmacological Characterization of a Novel TRPM8 Inhibitor Chemotype Identified by Small-Scale Preclinical Screening
7天前
已完结
Discovery of TRPM8 Antagonist (S)-6-(((3-Fluoro-4-(trifluoromethoxy)phenyl)(3-fluoropyridin-2-yl)methyl)carbamoyl)nicotinic Acid (AMG 333), a Clinical Candidate for the Treatment of Migraine
7天前
已完结
Metal ion-dependent hydrolysis of RNA phosphodiester bonds within hairpin loops. A comparative kinetic study on chimeric ribo/2'-O-methylribo oligonucleotides
16天前
已完结
Identification of a novel member of 2H phosphoesterases, 2ʹ,5ʹ-oligoadenylate degrading ribonuclease from the oyster Crassostrea gigas
16天前
已完结
Interconversion and phosphoester hydrolysis of 2',5'- and 3',5'-dinucleoside monophosphates: kinetics and mechanisms
16天前
已完结
Inheritance of acquired adaptive cold tolerance in rice through DNA methylation
20天前
已完结
Preclinical profiles of SKB264, a novel anti-TROP2 antibody conjugated to topoisomerase inhibitor, demonstrated promising antitumor efficacy compared to IMMU-132
20天前
已完结
Food effect trial of the pharmacokinetics and safety of TQ05105 in healthy Chinese subjects
25天前
已完结
A Phase I, Randomized, Double-Blind, Placebo-Controlled, Single Ascending Dose, Multiple Ascending Dose and Food Effect Study to Evaluate the Tolerance, Pharmacokinetics of Jaktinib, a New Selective Janus Kinase Inhibitor in Healthy Chinese Volunteers
25天前
已完结
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