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40 积分 2025-05-16 加入
PROTAC targeted protein degraders: the past is prologue
2天前
已完结
Sequential Disruption of Tumor Camouflage and Metabolic Coercion by Cascade-Acting Nano-Proteolysis Targeting Chimera Engines to Reprogram the Immune Ecosystem
3天前
已完结
Discovery of New OTUB1 Covalent Ligands via Structure-activity Relationship Studies for Targeted Protein Stabilization
26天前
已完结
A Novel FXR-Targeted DUBTAC and Its Applications in Cholestasis Therapy
1个月前
已完结
Targeted KRASG12V Degradation in vivo Elicits Lung Adenocarcinoma Regression with Subsequent Relapse from Dysregulated Proteolysis
2个月前
已完结
Harnessing the Deubiquitinase USP1 for Targeted Protein Stabilization
2个月前
已完结
Rezatapopt (PC14586): A First-in-Class Small Molecule p53 Y220C Mutant Protein Stabilizer in Clinical Trials
2个月前
已完结
Dual-targeting nanozyme combined with aPD-L1-based immunotherapy for combating cancer recurrence and metastasis
3个月前
已完结
The First‐In‐Class Deubiquitinase‐Targeting Chimera Stabilizes and Activates cGAS
3个月前
已完结
Hydrophobic/Amphiphilic Prodrug Coassembly Strategy: Exploring the Effect of Oligoethylene Glycol Chains on the Antitumor Efficacy of Nanoassemblies
4个月前
已完结
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