Lv1
40 积分 2025-09-11 加入
Design, synthesis, and biological profiling of novel aryl-spirocyclic diamine derivatives with potential antidepressant-like properties
1天前
待确认
Fine-tuning 5-HT7 receptor selectivity, inverse agonism, and metabolic stability of new (aryloxy)ethyl-piperidines toward antidepressant and pro-cognitive properties
1天前
已完结
Linker Methylation as a Strategy to Enhance PROTAC Oral Bioavailability: Insights from Molecular Properties and Conformational Analysis
1个月前
已完结
Overcoming E3 Ligase-Mediated Resistance: Development of Novel Hydrophobic Tagging-Based Degraders Targeting ALK Protein
1个月前
已完结
Sustained antidepressant actions of ketamine involve TAMM41-mediated transfer of astrocytic sigma-1 receptor to neuron
1个月前
已完结
Discovery of a Novel Orally Active Ketamine Derivative with Dual Analgesic and Antidepressant Activities, Lacking Psychomimetic Effects
1个月前
已完结
Pathway-selective 5-HT1AR agonist as a rapid antidepressant strategy
1个月前
已完结
UTILITIES AND LIMITATIONS OF CURRENT ANIMAL MODELS OF DEPRESSION
1个月前
已完结
Property-Based Design of Xanthine Derivatives as Potent and Orally Available TRPC4/5 Inhibitors for Depression and Anxiety
1个月前
已完结
Structural Rationalization of IPMK Inhibitor Potency
1个月前
已完结
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