Lv41
544 积分 2022-10-31 加入
Targeted degradation of Werner syndrome helicase (WRN) via ligand-directed covalent hydrophobic tagging
1小时前
已完结
Discovery of pyrrolopyrimidinone derivatives as potent PKMYT1 inhibitors for the treatment of cancer
1小时前
已完结
Design, synthesis, and structure−activity relationship studies of triazolo-pyrimidine derivatives as WRN inhibitors for the treatment of MSI tumors
2小时前
已完结
Discovery and optimization of thieno[3,2-d]pyrimidine derivatives as highly selective inhibitors of cyclin-dependent kinase 7
2小时前
已完结
Design and synthesis of 4th generation EGFR inhibitors against human triple (Del19/T790M/C797S) mutation
2小时前
已完结
What Do Oral Drugs Really Look Like? Dose Regimen, Pharmacokinetics, and Safety of Recently Approved Small-Molecule Oral Drugs
1个月前
已完结
Novel 6-aminofuro[3,2-c]pyridines as potent, orally efficacious inhibitors of cMET and RON kinases
3个月前
已完结
From lead to market: chemical approaches to transform peptides into therapeutics
3个月前
已完结
Iodine-Catalyzed Regioselective C-3 Chalcogenation of 7-Azaindoles: Access to Benzothiophene-Fused 7-Azaindole Analogs
4个月前
已完结
Synthesis of bisindolylmethane, bispyrrolylmethane, and indolylpyrrolylmethane derivatives via reductive heteroarylation
5个月前
已完结