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10 积分 2022-11-10 加入
Harnessing potential COX-2 engagement for boosting anticancer activity of substituted 2-mercapto-4(3H)-quinazolinones with promising EGFR/VEGFR-2 inhibitory activities
16小时前
已关闭
Discovery of novel pyrazole based Urea/Thiourea derivatives as multiple targeting VEGFR-2, EGFRWT, EGFRT790M tyrosine kinases and COX-2 Inhibitors, with anti-cancer and anti-inflammatory activities
16小时前
已完结
Dihydrotestosterone regulation of cyclooxygenase-2 expression in bovine endometrial epithelium cells by androgen receptor mediated EGFR/PI3K/Akt pathway
16小时前
已完结
Design, synthesis, and molecular dynamics-driven evaluation of quinoline-sulfonamide derivatives as potent and selective EGFR inhibitors with promising anti-cancer efficacy and safety profiles
16小时前
已完结
Design, synthesis and mechanistic studies of novel imidazo[1,2-a]pyridines as anticancer agents
17小时前
求助中
Design and synthesis of new pyrazole hybrids linked to oxime and nitrate moieties as COX-2, EGFRL858R/T790M inhibitors and nitric oxide donors with dual anti-inflammatory/anti-proliferative activities
17小时前
已关闭
Use of in silico and in vitro methods as a potential new approach methodologies (NAMs) for (photo)mutagenicity and phototoxicity risk assessment of agrochemicals
18小时前
已完结
Structural Analysis and Prediction of Hematotoxicity Using Deep Learning Approaches
1天前
已完结
In silico prediction of drug‐induced liver injury with a complementary integration strategy based on hybrid representation
1天前
已完结
The efficiency of multi-target drugs: the network approach might help drug design
6天前
已完结
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