Lv5
1510 积分 2025-08-26 加入
(+)-4-[2-[4-(8-Chloro-3,10-dibromo-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]- pyridin-11(R)-yl)-1-piperidinyl]-2-oxo-ethyl]-1-piperidinecarboxamide (SCH-66336): A Very Potent Farnesyl Protein Transferase Inhibitor as a Novel Antitumor Agent
1天前
已完结
Structure−Activity Relationship of 3-Substituted N-(Pyridinylacetyl)-4- (8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)- piperidine Inhibitors of Farnesyl-Protein Transferase: Design and Synthesis of in Vivo Active Antitumor Compounds
2天前
已完结
A Cereblon Modulator (CC-220) with Improved Degradation of Ikaros and Aiolos
8天前
已完结
Synthesis of the Key Intermediate of SM-406 (Xevinapant) and Its Analogues
9天前
已完结
Large Scale Practical Synthesis of Enantiomerically Pure cis-4-Amino-3-fluoro-1-methylpiperidine via Rhodium-Catalyzed Asymmetric Hydrogenation of a Tetrasubstituted Fluoroalkene
11天前
已完结
Practical Synthesis of an S1P Receptor Modulator via a Telescoped Three‑Step Oxidative Amination Sequence
11天前
已关闭
Development of the Convergent, Kilogram-Scale Synthesis of an Antibacterial Clinical Candidate Using Enantioselective Hydrogenation
11天前
已完结
A Versatile Method of Ambient-Temperature Solvent Removal
11天前
已完结
Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer
12天前
已完结
Identification of the Clinical Candidate (R)-(1-(4-Fluorophenyl)-6-((1-methyl-1H-pyrazol-4-yl)sulfonyl)-4,4a,5,6,7,8-hexahydro-1H-pyrazolo[3,4-g]isoquinolin-4a-yl)(4-(trifluoromethyl)pyridin-2-yl)methanone (CORT125134): A Selective Glucocorticoid Receptor (GR) Antagonist
30天前
已完结