Lv11
30 积分 2025-08-06 加入
Discovery of (10R)-7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro-2H-8,4-(metheno)pyrazolo[4,3-h][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile (PF-06463922), a Macrocyclic Inhibitor of Anaplastic Lymphoma Kinase (ALK) and c-ros Oncogene 1 (ROS1) with Preclinical Brain Exposure and Broad-Spectrum Potency against ALK-Resistant Mutations
3小时前
已完结
Acetone‐Linked Peptides: A Convergent Approach for Peptide Macrocyclization and Labeling
3小时前
已完结
FAP Radioligand Linker Optimization Improves Tumor Dose and Tumor-to-Healthy Organ Ratios in 4T1 Syngeneic Model
3小时前
已完结
Immobilized acyl-transfer molecular reactors enable the solid-phase synthesis of sterically hindered peptides
19天前
已完结
Small Organic Carbonic Anhydrase IX Ligands from DNA-Encoded Chemical Libraries for Tumor-Targeted Delivery of Radionuclides
20天前
已完结
皖公网安备34019202002308
