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46 积分 2024-01-27 加入
Chain-Shortened Myostatin Inhibitory Peptides Improve Grip Strength in Mice
1个月前
已完结
Design, synthesis, and structure−activity relationship studies of triazolo-pyrimidine derivatives as WRN inhibitors for the treatment of MSI tumors
1个月前
已完结
Discovery and optimization of potent covalent threonine tyrosine kinase (TTK) inhibitors for the treatment of triple-negative breast cancer
1个月前
已完结
Discovery of potent and selective PKMYT1 inhibitors for the treatment of CCNE1-amplified cancer
1个月前
已完结
Structure-based design, synthesis and bioactivity evaluation of macrocyclic inhibitors of mutant isocitrate dehydrogenase 2 (IDH2) displaying activity in acute myeloid leukemia cells
1个月前
已完结
Discovery of a brain-penetrant fourth-generation EGFR inhibitor to overcome the human triple (L858R/T790 M/C797S) mutation
1个月前
已完结
Discovery and optimization of thieno[3,2-d]pyrimidine derivatives as highly selective inhibitors of cyclin-dependent kinase 7
1个月前
已完结
Ligandability Assessment of IL-1β by Integrated Hit Identification Approaches
2个月前
已完结
515LBA (PB-515) LBA Posters: CID-078, a first-in-class oral macrocycle cyclin A/B-RxL inhibitor, demonstrates anti-tumor activity in E2F-driven cancers
2个月前
已完结
Design, synthesis and biological evaluation of novel cyano-cinnamate derivatives as mitochondrial pyruvate carrier inhibitors
3个月前
已完结
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