Lv62
2510 积分 2023-10-27 加入
Biotransformation of Daclatasvir In Vitro and in Nonclinical Species: Formation of the Main Metabolite by Pyrrolidine δ-Oxidation and Rearrangement
48分钟前
已完结
TRIM21-Driven Degradation of BRD4: Development of Heterobifunctional Degraders and Investigation of Recruitment and Selectivity Mechanisms
2小时前
待确认
Evolution of direct RAS inhibitors: from undruggable target to clinical breakthroughs
1天前
待确认
RIPTACs: A groundbreaking approach to drug discovery
7天前
已完结
Mutants of the tumour suppressor p53 L1 loop as second-site suppressors for restoring DNA binding to oncogenic p53 mutations: structural and biochemical insights
8天前
已完结
Bile Acid-Induced Aggregation and Phase Separation of Mutant p53 Leads to Doxorubicin Sequestration
11天前
已完结
PHASE: a new engine for pharmacophore perception, 3D QSAR model development, and 3D database screening: 1. Methodology and preliminary results
15天前
已完结
Linker-Driven Sampling of PROTAC-Induced Ternary Complexes
19天前
已完结
From Serendipity to Strategy: Rationalizing Molecular Glue Discovery and Proximity-Induced Pharmacology through Chemical Biology
21天前
已完结
Integrative structural and computational analysis reveals potential design principles for efficient PROTAC degraders
22天前
已完结