Lv11
56 积分 2023-08-11 加入
Enhancing siRNA efficacy in vivo with extended nucleic acid backbones
12天前
已完结
Expanding Conjugate Space of RNAi Therapeutics: Ligand at the 3′ End of the Antisense Strand Achieves Uncompromised In Vivo Potency and Efficacy and Reveals Interactions with the Argonaute‑2 PAZ Domain
13天前
已完结
Bifunctional LYTAC Mediates Hepatocytes-Hepatic Stellate Cells Crosstalk by Regulating 5‑HT2A Receptor Degradation and Antagonism to Synergistically Ameliorate Hepatic Fibrosis
20天前
已完结
Therapeutic RNA-silencing oligonucleotides in metabolic diseases
1个月前
已完结
Frameworks for transformational breakthroughs in RNA-based medicines
1个月前
已完结
RNA chemistry and therapeutics
1个月前
已完结
Tang, Q.; Khvorova, A. RNAi-Based Drug Design: Con siderations and Future Directions
1个月前
已完结
Enhancing siRNA efficacy in vivo with extended nucleic acid backbones
1个月前
已完结
Improved In Vivo Metabolic Stability and Silencing Efficacy of siRNAs with Phosphorothioate Linkage-Free, GalNAc-Conjugated Sense Strands Containing Morpholino-LNA Modifications
2个月前
已完结
S,X-Acetals in Nucleoside Chemistry. III1. Synthesis of 2′-and 3′-O-Azidomethyl Derivatives of Ribonucleosides
3个月前
已完结
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