Lv1
36 积分 2023-07-14 加入
Discovery of SY-589, a Highly Potent and Orally Bioavailable Polθ Helicase Inhibitor for the Treatment of HR-Deficient Tumors
2个月前
已完结
Targeting Protein Tyrosine Phosphatase Nonreceptor Type 2 with a Novel Inhibitor for the Treatment of Melanoma
5个月前
已完结
The PTPN2/PTPN1 Inhibitor Abbv-CLS-484 Augments Immune Responses Against Leukemic Blasts and Impedes Leukemia Cell Proliferation in AML Alone and in Combination with Venetoclax
7个月前
已关闭
Dual Conjugation of Long- and Medium-Chain Fatty Acids to BimBH3 Peptide Yields Ultra Long-Acting Inhibitors of Intracellular PTPN1/2
7个月前
已完结
The Oral CDK9 Inhibitor, TP-1287, Is Active in Non-Clinical Models of Multiple Myeloma
8个月前
已关闭
Novel Small-Molecule miR-124 Inducer Acts as “a Physiological Brake” of Inflammation in Ulcerative Colitis by Targeting the PIK3R2/PI3K/Akt Axis
8个月前
已完结
Design, Synthesis, and Antitumor Activity Evaluation of 2-Phenylthiazole-5-Carboxylic Acid Derivatives Targeting Transactivation Response RNA-Binding Protein 2
8个月前
已完结
Discovery of a Novel Selective and Cell-Active N6-Methyladenosine RNA Demethylase ALKBH5 Inhibitor
8个月前
已完结
Drug combination in vivo using combination index method: Taxotere and T607 against colon carcinoma HCT-116 xenograft tumor in nude mice
10个月前
已关闭
A combination of the geroprotectors trametinib and rapamycin is more effective than either drug alone
10个月前
已关闭