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54 积分 2023-07-07 加入
A comparison of the activity, lysosomal stability, and efficacy of legumain-cleavable and cathepsin-cleavable ADC linkers
3天前
已完结
Structure-Guided Discovery of Novel Highly Potent and Selective MTA-Cooperative PRMT5 Inhibitors
3天前
已完结
PRMT5: A Promising Synthetical Lethal Target for MTAP-Deleted Cancers
4天前
已完结
Design, synthesis and biological evaluation of camptothecin analogue FL118 as a payload for antibody-drug conjugates in targeted cancer therapy
15天前
已完结
Design of cathepsin-sensitive linkers for tumor-selective bioconjugate drug delivery
17天前
已完结
Degradation of GSPT1 causes TP53-independent cell death in leukemia while sparing normal hematopoietic stem cells
18天前
已完结
Exploiting synthetic lethality in PDAC with antibody drug conjugates and ATR inhibition
22天前
已完结
Mechanisms of resistance to antibody-drug conjugates in breast cancer
1个月前
已完结
Recent advances in the Total synthesis and structural modification of Ecteinascidin-743
1个月前
已完结
Metabolic Disposition of Lurbinectedin, a Potent Selective Inhibitor of Active Transcription of Protein-Coding Genes, in Nonclinical Species and Patients
2个月前
已完结
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