Lv1
36 积分 2021-05-21 加入
Fragment Optimization─Simple SMILES String Manipulation Strategies to Optimize a Hit or Fragment
4天前
已完结
Discovery of INCB127443: A Potent and Orally Available Inhibitor of Cyclin-Dependent Kinase 2
4天前
已完结
Optimising proteolysis-targeting chimeras (PROTACs) for oral drug delivery: a drug metabolism and pharmacokinetics perspective
7天前
已完结
Proteolysis Targeting Chimeras (PROTACs) in ‘Beyond Rule-of-Five’ Chemical Space: Recent Progress and Future Challenges
7天前
已完结
Beyond the Rule of 5: Lessons Learned from AbbVie’s Drugs and Compound Collection
7天前
已完结
Brain Penetration Optimization and Anti-neuroinflammation Evaluation of Potent 6-Methyl-7-azaindol-3-yl-quinazoline DYRK1A Inhibitors for Alzheimer’s Disease
7天前
已完结
An Integrated Approach Combining Receptor-Based Ensemble Screening and In Vivo Phenotypic Assessment Improves Drug-Induced Liver Injury Prediction
10天前
已完结
Leveraging Structure-Based Design to Overcome Class III RTK Off-Target Activity in the Development of Selective Wild-Type KIT Inhibitors
20天前
已完结
Deciphering interaction fingerprints from protein molecular surfaces using geometric deep learning
24天前
已完结
Deciphering interaction fingerprints from protein molecular surfaces using geometric deep learning
24天前
已完结
Investigating the Effects of Grammar Learning Strategies Instruction in CALL
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