Lv41
496 积分 2026-07-03 加入
Mechanism of the M. tuberculosis DprE1–DprE2 epimerase complex and inhibition by anti-tubercular drugs
1个月前
已完结
Discovery, Design, and Synthesis of Novel 2-Benzyl-2,7-diazaspiro[3.5]nonane Benzothiazinones with Broad-Spectrum Antimycobacterial Activity
1个月前
已关闭
Discovery of Potent Benzoselenazinone-Based DprE1 Inhibitors: A Novel Selenium-Containing Scaffold with Superior Anti-TB Activity and Pharmacokinetic Properties
1个月前
已完结
Design and discovery of 1,4-dihydropyrimidinone-based noncovalent DprE1 inhibitors with integrated biological and computational validation against Mycobacterium tuberculosis
1个月前
已完结
Discovery of Effective Dual PROTAC Degraders with Synergistic Antitumor Activity for Overcoming Tamoxifen-Resistant Breast Cancer
1个月前
已完结
Identification of a Potent and Selective Small-Molecule Inhibitor Targeting the nNOS-PDZ Domain that Exhibits Rapid In Vivo Antidepressant Efficacy
3个月前
已完结
Design, Synthesis, and Antitubercular Activity Evaluation of Novel Nitroimidazole Derivatives
3个月前
已关闭
Development of pyrazolo[1,5-a]pyrimidine-grafted coumarins as selective carbonic anhydrase inhibitors and tubulin polymerization inhibitors with potent anticancer activity
3个月前
已关闭
Discovery of new sulfonamide-tethered 2-aryl-4-anilinoquinazolines as the first-in-class dual carbonic anhydrase and EGFR inhibitors
3个月前
已关闭
Development of pyrazolo[1,5-a]pyrimidine-grafted coumarins as selective carbonic anhydrase inhibitors and tubulin polymerization inhibitors with potent anticancer activity
3个月前
已关闭
皖公网安备34019202002308
