Lv41
648 积分 2025-05-27 加入
Discovery of Highly Potent and Selective, Orally Bioavailable BTK-Targeting PROTACs Featuring Novel CRBN-Binding Warheads
9小时前
已完结
Novel selective agents for the degradation of AR/AR-V7 to treat advanced prostate cancer
1个月前
已完结
SHR2554, an EZH2 inhibitor, in relapsed or refractory mature lymphoid neoplasms: a first-in-human, dose-escalation, dose-expansion, and clinical expansion phase 1 trial
2个月前
已完结
Benzothiophene-based, orally active PIK3CA H1047R mutant-selective inhibitors for the treatment of HR+/HER2- breast cancer
2个月前
已完结
Preclinical characterization of TOS-358, a potent and selective covalent inhibitor of wild-type and mutant PI3Kα with superior anticancer activity
2个月前
已完结
Core-shell lipoplexes inducing active macropinocytosis promote intranasal delivery of c-Myc siRNA for treatment of glioblastoma
2个月前
已完结
Small-molecule inhibitors of the Myc oncoprotein
3个月前
已完结
Functional interactions among members of the MAX and MLX transcriptional network during oncogenesis
3个月前
已完结
MYC, MYCL, and MYCN as therapeutic targets in lung cancer
3个月前
已完结
Myc proteins in cell biology and pathology
3个月前
已完结
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