Lv11
70 积分 2024-03-25 加入
Relocalizing transcriptional kinases to activate apoptosis
1小时前
已完结
Discovery of novel JAK3 inhibitors for the treatment of atopic dermatitis
12天前
已完结
Cyclins and cyclin-dependent kinases: from biology to tumorigenesis and therapeutic opportunities
14天前
已完结
Design, synthesis, and biological evaluation of N-(2-amino-phenyl)-5-(4-aryl- pyrimidin-2-yl) amino)-1H-indole-2-carboxamide derivatives as novel inhibitors of CDK9 and class I HDACs for cancer treatment
23天前
已完结
Discovery of Novel 2-Aminopyridine-Based and 2-Aminopyrimidine-Based Derivatives as Potent CDK/HDAC Dual Inhibitors for the Treatment of Refractory Solid Tumors and Hematological Malignancies
23天前
已完结
Design, synthesis and biological evaluation of dual CDK9/PARP inhibitors for the treatment of cancer
23天前
已完结
From Structure Modification to Drug Launch: A Systematic Review of the Ongoing Development of Cyclin-Dependent Kinase Inhibitors for Multiple Cancer Therapy
29天前
已完结
EEDi-5285: An Exceptionally Potent, Efficacious, and Orally Active Small-Molecule Inhibitor of Embryonic Ectoderm Development
1个月前
已完结
An allosteric PRC2 inhibitor targeting the H3K27me3 binding pocket of EED
1个月前
已完结
Discovery and preclinical profile of YK-2168, a differentiated selective CDK9 inhibitor in clinical development
2个月前
已完结
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