Lv1
60 积分 2024-03-25 加入
Discovery of selective PARP1/EZH2 inhibitor inducing PANoptosis in triple-negative breast cancer
15天前
已完结
Design, synthesis and biological evaluation of dual CDK9/PARP inhibitors for the treatment of cancer
15天前
已完结
Dual target PARP1/EZH2 inhibitors inducing excessive autophagy and producing synthetic lethality for triple-negative breast cancer therapy
1个月前
已完结
Relocalizing transcriptional kinases to activate apoptosis
2个月前
已完结
Discovery of novel JAK3 inhibitors for the treatment of atopic dermatitis
2个月前
已完结
Cyclins and cyclin-dependent kinases: from biology to tumorigenesis and therapeutic opportunities
2个月前
已完结
Design, synthesis, and biological evaluation of N-(2-amino-phenyl)-5-(4-aryl- pyrimidin-2-yl) amino)-1H-indole-2-carboxamide derivatives as novel inhibitors of CDK9 and class I HDACs for cancer treatment
2个月前
已完结
Discovery of Novel 2-Aminopyridine-Based and 2-Aminopyrimidine-Based Derivatives as Potent CDK/HDAC Dual Inhibitors for the Treatment of Refractory Solid Tumors and Hematological Malignancies
2个月前
已完结
Design, synthesis and biological evaluation of dual CDK9/PARP inhibitors for the treatment of cancer
2个月前
已完结
From Structure Modification to Drug Launch: A Systematic Review of the Ongoing Development of Cyclin-Dependent Kinase Inhibitors for Multiple Cancer Therapy
2个月前
已完结