Lv1
18 积分 2025-01-21 加入
Discovery of Novel Oral Covalent Inhibitors Targeting Active GTP-Bound KRASG12C with Potent Antitumor Activity
11小时前
求助中
A three-dimensional pharmacophore modelling of ITK inhibitors and virtual screening for novel inhibitors
10天前
已完结
Discovery and SAR of 2-amino-5-[(thiomethyl)aryl]thiazoles as potent and selective Itk inhibitors
10天前
已完结
Biological Activity and Structural Biology of Current KAT6A Inhibitor Chemotypes
18天前
已完结
Discovery of Potent and Selective Covalent Inhibitors of HER2WT and HER2YVMA
1个月前
已完结
Design of a Janus Kinase 3 (JAK3) Specific Inhibitor 1-((2S,5R)-5-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one (PF-06651600) Allowing for the Interrogation of JAK3 Signaling in Humans
1个月前
已完结
Overcoming Resistance in EGFR-Mutant Cancers: A Comprehensive Review of Inhibitor Evolution and SAR-Based Design
1个月前
已完结
Late-stage functionalization with strain-release warheads enables tunable covalent inhibition
1个月前
已完结
Increase Docking Score Screening Power by Simple Fusion With CNNscore
5个月前
已完结
Viral Entry Inhibitors Targeting Six-Helical Bundle Core against Highly Pathogenic Enveloped Viruses with Class I Fusion Proteins
10个月前
已完结
Dietary intervention enhances fertility in obese male mice by regulating SLC2As
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