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350 积分 2025-03-16 加入
Lymphatic-localized Treg-mregDC crosstalk limits antigen trafficking and restrains anti-tumor immunity
6天前
已完结
YTHDC1 is a therapeutic target for B-cell acute lymphoblastic leukemia by attenuating DNA damage response through the KMT2C-H3K4me1/me3 epigenetic axis
28天前
已完结
YTHDC1 cooperates with the THO complex to prevent RNA damage-induced DNA breaks
1个月前
已完结
Discovery of SD-436: A Potent, Highly Selective and Efficacious STAT3 PROTAC Degrader Capable of Achieving Complete and Long-Lasting Tumor Regression
1个月前
已完结
A STAT3 Degrader Demonstrates Pre-clinical Efficacy in Venetoclax resistant Acute Myeloid Leukemia
1个月前
已完结
Targeting the STAT3 pathway with STAT3 degraders
1个月前
已完结
PROTAC protein degraders to drug the undruggable enter phase 3 trials
1个月前
已完结
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