Lv11
32 积分 2024-10-22 加入
New payloads drive next-gen antibody-drug conjugates
9小时前
待确认
Preclinical Development of MGC028, an ADAM9-Targeted, Glycan-Linked, Exatecan-Based Antibody–Drug Conjugate for the Treatment of Solid Cancers
22天前
已完结
BCMA and GPRC5D/FcRH5 bispecific antibodies have different AE profiles
4个月前
已完结
Transforming toxins into treatments: the revolutionary role of α-amanitin in cancer therapy
4个月前
已完结
Discovery and Preclinical Evaluation of PBX-7016, a Methylenedioxy-Camptothecin Payload for Antibody-Drug Conjugates with Enhanced Therapeutic Potential
5个月前
已完结
Design, synthesis and biological evaluation of camptothecin analogue FL118 as a payload for antibody-drug conjugates in targeted cancer therapy
5个月前
已完结
Ramantamig (JNJ-79635322), a novel T-cell-engaging trispecific antibody targeting BCMA, GPRC5D, and CD3, in multiple myeloma models
5个月前
已完结
Pharmacological, computational, and mechanistic insights into triptolide’s role in targeting drug-resistant cancers
5个月前
已完结
Functional patient-derived organoid screenings identify MCLA-158 as a therapeutic EGFR × LGR5 bispecific antibody with efficacy in epithelial tumors
6个月前
已完结
HER3 upregulation reduces DS-8201 sensitivity in HER2-positive tumor cells by ATR/CHK1/FoxO1 signaling cascade
6个月前
已完结
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