Lv23
194 积分 2026-04-02 加入
Enantioselective synthesis of 1,3-bicyclo[2.1.1]hexanes as meta-benzene bioisosteres
6天前
已完结
Unraveling the Role of Linker Design in Proteolysis Targeting Chimeras
13天前
已完结
Optimization of Azaspirooxindolinone-based PROTACs targeting BTK: Synthesis, kinase profiling, and degradation analysis
21天前
已关闭
Branching beyond bifunctional linkers: synthesis of macrocyclic and trivalent PROTACs
21天前
已完结
Smallest Bicycles in Medicinal Chemistry: Where Are We Now?
23天前
已完结
Amide Bond Bioisosteres: Strategies, Synthesis, and Successes
1个月前
已完结
Beyond Bioisosteres: Impact of Replacing a Benzene Ring with sp 3 -Rich Three-Dimensional Saturated Bridged Bicyclic Match Pairs on Biotransformation, Metabolic Stability, and Other ADME Profiles
1个月前
已完结
Discovery of novel BTK PROTACs with improved metabolic stability via linker rigidification strategy
1个月前
已完结
Discovery of Novel Bruton’s Tyrosine Kinase PROTACs with Enhanced Selectivity and Cellular Efficacy
1个月前
已完结
Discovery of novel BTK PROTACs for B-Cell lymphomas
1个月前
已完结
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