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Discovery of Tetracyclic Derivatives as Highly Potent, Selective, and Bioavailable PKMYT1 Inhibitors for Cancer Therapy
1个月前
已完结
Conformational restriction of hinge carboxamide leading to potent lactam-based PKMYT1 inhibitors
1个月前
已完结
Route Design, Process Development, and Manufacture of XL495: An Atropisomeric PKMYT1 Inhibitor
1个月前
已完结
Targeting Protein Kinase, Membrane-Associated Tyrosine/Threonine 1 (PKMYT1) for Precision Cancer Therapy: From Discovery to Clinical Trial
1个月前
已完结
Myt1 kinase inhibitors - Insight into structural features, offering potential frameworks
1个月前
已完结
Synthesis and study the pharmacological activity of derivatives of 5-dimethylaminopyrano[3,2-c]quinolin-2-ones
1个月前
已完结
Discovery of Naphthyridinone Derivatives as Selective PKMYT1/WEE1 Dual Inhibitors for Cancer Therapy
2个月前
已完结
Discovery of CMNPD31124 as a novel marine-derived PKMYT1 inhibitor for pancreatic ductal adenocarcinoma therapy: computational and biological insights
2个月前
已完结
Allosteric Inhibition of PKMYT1 Induces a Unique, Inactive ATP Binding Site Conformation
2个月前
已完结
Synthesis of Pyridoxine-Derived Dimethylpyridinols Fused with Aminooxazole, Aminoimidazole, and Aminopyrrole
2个月前
已完结
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