Lv21
114 积分 2025-10-14 加入
Two Mechanisms OneMolecule: Developing a ‘Truly’Bifunctional Degrader Targeting Rpn13 and CRBN
2小时前
待确认
A bivalent molecular glue linking lysine acetyltransferases to oncogene-induced cell death
1个月前
已完结
Discovery of Highly Potent, Selective, and Orally Efficacious p300/CBP Histone Acetyltransferases Inhibitors
2个月前
已完结
Acetylation-dependent nuclear translocation of EXOC4 regulates KU70 methylation to facilitate non-homologous end joining
2个月前
已完结
A PROTAC-inspired bifunctional small molecule recruits CDK6 to target EYA2 degradation and suppress breast tumor growth
2个月前
已完结
SETDB1 promotes gastric carcinogenesis and metastasis via upregulation of CCND1 and MMP9 expression
2个月前
已完结
Determining the Substrate Specificity of Lysine Methyltransferases
2个月前
已完结
The HSP90-dependent bioorthogonal PROTAC prodrug system enables tumor-selective and enhanced protein degradation
3个月前
已完结
Acyltransferase ZDHHC22 promotes N-Myc transcriptional activation to drive neuroblastoma progression and chemoresistance
3个月前
已完结
Hijacking ERAD for targeted degradation of transmembrane proteins
5个月前
已完结
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