Lv2
116 积分 2025-10-14 加入
Discovery of Highly Potent, Selective, and Orally Efficacious p300/CBP Histone Acetyltransferases Inhibitors
2天前
已完结
Acetylation-dependent nuclear translocation of EXOC4 regulates KU70 methylation to facilitate non-homologous end joining
2天前
已完结
A PROTAC-inspired bifunctional small molecule recruits CDK6 to target EYA2 degradation and suppress breast tumor growth
6天前
已完结
SETDB1 promotes gastric carcinogenesis and metastasis via upregulation of CCND1 and MMP9 expression
21天前
已完结
Determining the Substrate Specificity of Lysine Methyltransferases
22天前
已完结
The HSP90-dependent bioorthogonal PROTAC prodrug system enables tumor-selective and enhanced protein degradation
1个月前
已完结
Acyltransferase ZDHHC22 promotes N-Myc transcriptional activation to drive neuroblastoma progression and chemoresistance
1个月前
已完结
Hijacking ERAD for targeted degradation of transmembrane proteins
2个月前
已完结
CD44‐Assisted Transcytosable Chimeras for Extracellular Protein Depletion in Deep Tumors
3个月前
已完结
Membrane‐Bounded Intracellular E3 Ubiquitin Ligase‐Targeting Chimeras (MembTACs) for Targeted Membrane Protein Degradation
7个月前
已完结
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