Lv53
1008 积分 2023-11-09 加入
CDK2 heterobifunctional degraders co-degrade CDK2 and cyclin E resulting in efficacy in CCNE1-amplified and overexpressed cancers
1天前
待确认
Structure–activity relationships of carboxymethylpullulan-peptide-doxorubicin conjugates—systematic modification of peptide spacers
23天前
已完结
Synthesis, structure–activity relationship and biological evaluation of 2,4,5-trisubstituted pyrimidine CDK inhibitors as potential anti-tumour agents
1个月前
已关闭
Molecular and pharmacodynamic characteristics of the novel multi-target tumor growth inhibitor ZK 304709
1个月前
已完结
Design of wogonin-inspired selective cyclin-dependent kinase 9 (CDK9) inhibitors with potent in vitro and in vivo antitumor activity
1个月前
已完结
Development and structure-activity relationship of tacrine derivatives as highly potent CDK2/9 inhibitors for the treatment of cancer
1个月前
已完结
A new cyclin-dependent kinase-9 inhibitor A09-003 induces apoptosis in acute myeloid leukemia cells with reduction of myeloid cell leukemia sequence-1 protein
1个月前
已完结
Design, synthesis and biological assessment of novel CDK4 inhibitor with potent anticancer activity
1个月前
已完结
Design, synthesis and biological evaluation of novel pyridine-thiazolidinone derivatives as anticancer agents: Targeting human carbonic anhydrase IX
1个月前
已关闭
The selective P-TEFb inhibitor CAN508 targets angiogenesis
1个月前
已完结
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