Lv61
1880 积分 2022-03-08 加入
Metabolic Activation of the Acrylamide Michael Acceptor Warhead in Futibatinib to an Epoxide Intermediate Engenders Covalent Inactivation of CYP3A
26天前
已完结
Fraction Unbound for Liver Microsome and Hepatocyte Incubations for All Major Species Can Be Approximated Using a Single-Species Surrogate
2个月前
已完结
Method development and validation for simultaneous determination of six tyrosine kinase inhibitors and two active metabolites in human plasma/serum using UPLC–MS/MS for therapeutic drug monitoring
2个月前
已完结
Red Blood Cells: A Neglected Compartment in Pharmacokinetics and Pharmacodynamics
3个月前
已完结
The Effects of Haematocrit, Plasma Protein Concentration and Temperature of Drug-containing Blood In-vitro on the Concentrations of the Drug in the Plasma
3个月前
已关闭
Radioactive ADME Demonstrates ARV-110’s High Druggability Despite Low Oral Bioavailability
4个月前
已完结
Examining the Uptake of Central Nervous System Drugs and Candidates across the Blood-Brain Barrier
4个月前
已关闭
Preclinical metabolism and disposition of [ 14 C]GFH009, a novel selective CDK9 inhibitor
6个月前
已完结
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