Lv5
1144 积分 2026-01-05 加入
From Structure to Selectivity: Integrating CADD and AIDD in Rational Medicinal Chemistry Strategies for DYRK1A Inhibitor Discovery
1个月前
已完结
Discovery of Novel Isoxazole-Based FXR Agonists Containing a 1,2,4-Oxadiazol-5(4H)-one Ring
1个月前
已完结
Identification and Validation of 3-Cyano-Quinoline Ligands Targeting Integrin-Linked Kinase (ILK)
1个月前
已完结
Discovery of Jatrophane Diterpenoids as JAG1-Notch Signaling Inhibitors for the Treatment of Liver Fibrosis
1个月前
已完结
Synthesis and Biological Evaluation of a New Dihydroceramide Desaturase Inhibitor for the Treatment of MASLD
1个月前
已完结
Targeted antibody-drug conjugates for rhabdomyosarcoma and other FGFR4-expressing cancers
1个月前
已完结
Stability and Degradation-based Proteome Profiling Reveals Cannabidiol as a Promising CDC123-eIF2γ Inhibitor for Colorectal Cancer Therapy
1个月前
已完结
Discovery of a Structurally Distinct Acetylenase in the Biosynthesis of Mangotoxin
1个月前
已完结
Total Synthesis of Euphopia B and Discovery of a Selective Inhibitor of Potassium Efflux-Independent NLRP3 Inflammasome Activation
1个月前
已完结
Mechanistic Insights into a Classic Wonder Drug—Aspirin
1个月前
已完结