Lv4
414 积分 2025-12-31 加入
Determination of Intrinsic Clearance and Fraction Unbound in Human Liver Microsomes and In Vitro-In Vivo Extrapolation of Human Hepatic Clearance for Marketed Central Nervous System Drugs
13天前
已完结
Pharmacological profile of CS-3150, a novel, highly potent and selective non-steroidal mineralocorticoid receptor antagonist
14天前
已关闭
CS-3150, a novel non-steroidal mineralocorticoid receptor antagonist, prevents hypertension and cardiorenal injury in Dahl salt-sensitive hypertensive rats
14天前
已完结
Structural determinants of activation of the mineralocorticoid receptor: an evolutionary perspective
15天前
已完结
In vitro and in vivo preclinical pharmacokinetic characterization of aficamten, a small molecule cardiac myosin inhibitor
1个月前
已完结
Assaying the myosin super-relaxed state across muscle types, cells and proteins for understanding muscle biology and use in drug discovery
1个月前
已完结
Clinical and Molecular Genetics of the Phosphodiesterases (PDEs)
2个月前
已完结
Screening oral drugs for their interactions with the intestinal transportome via porcine tissue explants and machine learning
2个月前
已完结
Strategic Design of Triple GLP-1R/GCGR/GIPR Agonists with Varied Receptor Potency: Achieving Comparable Glycemic and Weight Reduction Effects
2个月前
已完结
Variant screening of PYY 3–36 leads to potent long-acting PYY analogs with superior Y 2 receptor selectivity
3个月前
已完结
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