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30 积分 2025-11-08 加入
Recent advances in adamantane-linked heterocycles: synthesis and biological activity
5天前
已完结
Advances in targeting p38 MAPK for cancer therapy: insights from molecular pharmacology and medicinal chemistry
5天前
已完结
Vasicine derivatives as potent MAPK inhibitors for psoriasis treatment
5天前
已完结
Synthesis of structurally diverse thiazole-fused indole derivatives via a one-pot four-component cascade reaction
5天前
已完结
AI-driven discovery of natural product-derived FAK1 inhibitors for idiopathic pulmonary fibrosis
5天前
已完结
Abstract 4514: Discovery of potent and orally bioavailable degraders of HPK1 based on a novel HPK1 binder
3个月前
已关闭
969 HZ-S109, a potent and selective HPK1 degrader with enhanced T cell modulation efficacy and improved bioavailability
3个月前
已关闭
Abstract 5541: BGB-15025, a potent and selective HPK1 inhibitor, is efficacious as a single agent or in combination with PD-1 antibody in multiple tumor models
3个月前
已完结
489 TWT-101: a phase 1 study of the novel HPK1 inhibitor CFI-402411 in patients with advanced cancer
3个月前
已关闭
Discovery of 1(2H)-phthalazinone and 1(2H)-isoquinolinone derivatives as potent hematopoietic progenitor kinase 1 (HPK1) inhibitors
3个月前
已完结
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