Lv5
1324 积分 2024-04-23 加入
Targeted protein degradation using the lysosomal pathway
5天前
已完结
Development and Execution of a Scalable Route to an Immunology ADC Drug-Linker for ABBV-154
11天前
已完结
Systematic Evaluation of Maleimide Spacer Impact on Drug-Linker Deconjugation in Antibody-Drug Conjugates Ex Vivo and In Vivo
13天前
已完结
Trastuzumab-MMAU Antibody-Auristatin Conjugates: Valine-Glucoserine Linker with Stabilized Maleimide Conjugation Improves In Vivo Efficacy and Tolerability
16天前
已完结
Receptor-ubiquitination-targeting antibody-drug conjugates for enhanced endocytosis and lysosomal delivery
19天前
已关闭
Site-specific C-terminal and internal loop labeling of proteins using sortase-mediated reactions
19天前
已完结
Structure−Activity relationship study of benzothiophene oxobutanoic acid analogues leading to novel stimulator of interferon gene (STING) agonists
19天前
已完结
Aryl Sulfate is a Useful Motif for Conjugating and Releasing Phenolic Molecules: Sulfur Fluorine Exchange Click Chemistry Enables Discovery of Ortho-Hydroxy-Protected Aryl Sulfate Linker
30天前
已完结
An orally available non-nucleotide STING agonist with antitumor activity
1个月前
已完结
Synthetic Site-Specific Antibody–Ligand Conjugates Promote Asialoglycoprotein Receptor-Mediated Degradation of Extracellular Human PCSK9
1个月前
已完结
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