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Antibiotics-Induced Depletion of Rat Microbiota Induces Changes in the Expression of Host Drug-Processing Genes and Pharmacokinetic Behaviors of CYPs Probe Drugs
13天前
已完结
Identification and Functional Assessment of Eight CYP3A4 Allelic Variants *39–*46 Detected in the Chinese Han Population
2个月前
已完结
CYP3A4 and CYP2C19 genetic polymorphisms and myricetin interaction on tofacitinib metabolism
2个月前
已完结
Effects of Cytochrome P450 enzymes and drug–drug interaction on donafenib metabolism: in vivo, in vitro and in silico
3个月前
已完结
Screening of 16 major drug glucuronides for time-dependent inhibition of nine drug-metabolizing CYP enzymes – detailed studies on CYP3A inhibitors
4个月前
已完结
Time-dependent inactivation of human cytochrome P450 2A6 variants and 2A13 by imperatorin: natural coumarins and imperatorin oxidation
4个月前
已完结
Functional assessment of CYP3A4 and CYP2C19 genetic polymorphisms on the metabolism of clothianidin in vitro
4个月前
已完结
Exploring potential targets and molecular mechanisms of traumatic brain injury exacerbated by Benzo(a)pyrene via network toxicology and molecular dynamics simulation
5个月前
已完结
ABCB1 and ABCG2 limit brain penetration and, together with CYP3A4, total plasma exposure of abemaciclib and its active metabolites
5个月前
已完结
ABCB1 and ABCG2 limit brain penetration and, together with CYP3A4, total plasma exposure of abemaciclib and its active metabolites
5个月前
已完结