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20 积分 2024-06-30 加入
Mechanism-Based Inactivation of CYP2D6 by Phellopterin and Related Drug–Drug Interaction with Metoprolol
27天前
已完结
A framework for optimized reaction phenotyping of the seven major hepatic P450 isoforms in human liver microsomes using six mechanism-based inactivators and one reversible inhibitor
27天前
已关闭
Simultaneous determination of BGT-002 and its acyl glucuronide metabolite ZM326E-M2 in human plasma by liquid chromatography-tandem mass spectrometry and its application to a pharmacokinetic study
1个月前
已完结
Antibiotics-Induced Depletion of Rat Microbiota Induces Changes in the Expression of Host Drug-Processing Genes and Pharmacokinetic Behaviors of CYPs Probe Drugs
3个月前
已完结
Identification and Functional Assessment of Eight CYP3A4 Allelic Variants *39–*46 Detected in the Chinese Han Population
6个月前
已完结
CYP3A4 and CYP2C19 genetic polymorphisms and myricetin interaction on tofacitinib metabolism
6个月前
已完结
Effects of Cytochrome P450 enzymes and drug–drug interaction on donafenib metabolism: in vivo, in vitro and in silico
6个月前
已完结
Screening of 16 major drug glucuronides for time-dependent inhibition of nine drug-metabolizing CYP enzymes – detailed studies on CYP3A inhibitors
7个月前
已完结
Time-dependent inactivation of human cytochrome P450 2A6 variants and 2A13 by imperatorin: natural coumarins and imperatorin oxidation
7个月前
已完结
Functional assessment of CYP3A4 and CYP2C19 genetic polymorphisms on the metabolism of clothianidin in vitro
8个月前
已完结
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