Lv11
10 积分 2024-06-30 加入
Simultaneous determination of BGT-002 and its acyl glucuronide metabolite ZM326E-M2 in human plasma by liquid chromatography-tandem mass spectrometry and its application to a pharmacokinetic study
1小时前
已完结
Antibiotics-Induced Depletion of Rat Microbiota Induces Changes in the Expression of Host Drug-Processing Genes and Pharmacokinetic Behaviors of CYPs Probe Drugs
2个月前
已完结
Identification and Functional Assessment of Eight CYP3A4 Allelic Variants *39–*46 Detected in the Chinese Han Population
4个月前
已完结
CYP3A4 and CYP2C19 genetic polymorphisms and myricetin interaction on tofacitinib metabolism
4个月前
已完结
Effects of Cytochrome P450 enzymes and drug–drug interaction on donafenib metabolism: in vivo, in vitro and in silico
4个月前
已完结
Screening of 16 major drug glucuronides for time-dependent inhibition of nine drug-metabolizing CYP enzymes – detailed studies on CYP3A inhibitors
6个月前
已完结
Time-dependent inactivation of human cytochrome P450 2A6 variants and 2A13 by imperatorin: natural coumarins and imperatorin oxidation
6个月前
已完结
Functional assessment of CYP3A4 and CYP2C19 genetic polymorphisms on the metabolism of clothianidin in vitro
6个月前
已完结
Exploring potential targets and molecular mechanisms of traumatic brain injury exacerbated by Benzo(a)pyrene via network toxicology and molecular dynamics simulation
7个月前
已完结
ABCB1 and ABCG2 limit brain penetration and, together with CYP3A4, total plasma exposure of abemaciclib and its active metabolites
7个月前
已完结
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