Lv51
1465 积分 2021-08-29 加入
Discovery of a Novel Non-invasive AR PROTAC Degrader for the Topical Treatment of Androgenetic Alopecia
18分钟前
待确认
A chemical probe to modulate human GID4 Pro/N-degron interactions
4小时前
待确认
Selective and Potent Molecular Glue Degraders for NIMA‐Related Kinase 7
3天前
已完结
High-Throughput Cellular Profiling of Targeted Protein Degradation Compounds Using HiBiT CRISPR Cell Lines
8天前
已关闭
Discovery of KT-474─a Potent, Selective, and Orally Bioavailable IRAK4 Degrader for the Treatment of Autoimmune Diseases
13天前
已完结
Targeting HDAC3, a new partner protein of AKT in the reversal of chemoresistance in acute myeloid leukemia via DNA damage response
22天前
已完结
Discovery of Highly Potent and Orally Bioavailable Histone Deacetylase 3 Inhibitors as Immunomodulators and Enhancers of DNA-Damage Response in Cancer Therapy
22天前
已完结
HDAC1 acts as a tumor suppressor in ALK-positive anaplastic large cell lymphoma: implications for HDAC inhibitor therapy
22天前
已完结
UM171 glues asymmetric CRL3–HDAC1/2 assembly to degrade CoREST corepressors
22天前
已完结
The protein deacetylase HDAC10 controls DNA replication in malignant lymphoid cells
22天前
已完结
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