Lv4
545 积分 2021-08-29 加入
Development of a sensitive luminescent probe to uncover new BRD4 inhibitors in living cells
21小时前
待确认
Diving into the Water: Inducible Binding Conformations for BRD4, TAF1(2), BRD9, and CECR2 Bromodomains
2天前
已完结
GNE-371, a Potent and Selective Chemical Probe for the Second Bromodomains of Human Transcription-Initiation-Factor TFIID Subunit 1 and Transcription-Initiation-Factor TFIID Subunit 1-like
2天前
已完结
PROTAC-Mediated Degradation of TAF1 Induces Apoptosis in AML Cells and Inhibits Tumor Growth In Vivo
2天前
已完结
Discovery of SMD-6346: A Potent, Selective, and Orally Active SMARCA2 Degrader for Targeting SMARCA4-Deficient Human Cancers
2天前
已完结
State-selective small molecule degraders that preferentially remove aggregates and oligomers
3天前
已完结
Selective CDK2 Degradation via Noncanonical Recruitment
3天前
已完结
Innate Immune Signaling Organelles Display Natural and Programmable Signaling Flexibility
4天前
已完结
Acetylation Targeting Chimera Enables Acetylation of the Tumor Suppressor p53
11天前
已完结
Discovery of CW-3308 as a Potent, Selective, and Orally Efficacious PROTAC Degrader of BRD9
21天前
已完结