Lv42
684 积分 2021-12-13 加入
Discovery of Potent Small-Molecule Inhibitors of WDR5-MYC Interaction
1小时前
已完结
Discovery and Structure-Based Design of Inhibitors of the WD Repeat-Containing Protein 5 (WDR5)–MYC Interaction
2小时前
已完结
Discovery of Novel Inhibitors for WD Repeat‐Containing Protein 5 (WDR5)‐MYC Protein–Protein Interaction
2小时前
已完结
Structure and Ligand-Based Design of mTOR and PI3-Kinase Inhibitors Leading to the Clinical Candidates VS-5584 (SB2343) and SB2602
16天前
已完结
Structural Insights into the Development of Inhibitors Against Cancer-Specific Mutations of PI3Kα
29天前
已完结
Inavolisib-Based Therapy in PIK3CA -Mutated Advanced Breast Cancer
29天前
已完结
Discovery of GDC-0077 (Inavolisib), a Highly Selective Inhibitor and Degrader of Mutant PI3Kα
29天前
已完结
Designed peptide binders and nanobodies as PROTAC starting points for targeted degradation of PCNA and BCL6
1个月前
已完结
The Discovery of MORF-627, a Highly Selective Conformationally-Biased Zwitterionic Integrin αvβ6 Inhibitor for Fibrosis
1个月前
已完结
Rational Design of PARP1/c-Met Dual Inhibitors for Overcoming PARP1 Inhibitor Resistance Induced by c-Met Overexpression
1个月前
已完结
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