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22 积分 2025-02-21 加入
H1152 promotes the degradation of polyglutamine-expanded ataxin-3 or ataxin-7 independently of its ROCK-inhibiting effect and ameliorates mutant ataxin-3-induced neurodegeneration in the SCA3 transgenic mouse
23小时前
已完结
Ataxin-3 Interactions with Rad23 and Valosin-Containing Protein and Its Associations with Ubiquitin Chains and the Proteasome Are Consistent with a Role in Ubiquitin-Mediated Proteolysis
1天前
已关闭
Role of increased expression of the proteasome in the protective effects of sulforaphane against hydrogen peroxide-mediated cytotoxicity in murine neuroblastoma cells
5天前
已完结
[24] Membrane filter assay for detection of amyloid-like polyglutamine-containing protein aggregates
12天前
已完结
Divalproex sodium modulates nuclear localization of ataxin‐3 and prevents cellular toxicity caused by expanded ataxin‐3
12天前
已完结
Agouti Related Peptide Secreted Via Human Mesenchymal Stem Cells Upregulates Proteasome Activity in an Alzheimer’s Disease Model
21天前
已完结
Lignin-carbohydrate complexes suppress SCA3 neurodegeneration via upregulating proteasomal activities
1个月前
已完结
Trehalose prevents the formation of aggregates of mutant ataxin-3 and reduces soluble ataxin-3 protein levels in an SCA3 cell model
1个月前
已完结
Enhanced Degradation of Mutant C9ORF72-Derived Toxic Dipeptide Repeat Proteins by 20S Proteasome Activation Results in Restoration of Proteostasis and Neuroprotection
1个月前
已完结
Extracellular Vesicle‐Mediated Delivery of 20S Proteasomes Enhances Tau Degradation in Recipient Cells
1个月前
已完结
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