Lv31
252 积分 2024-12-26 加入
Visualizing agonist-induced M2 receptor activation regulated by aromatic ring dynamics
7小时前
待确认
Identification of two distinct inactive conformations of the β 2 -adrenergic receptor reconciles structural and biochemical observations
19天前
已完结
Cloud-based simulations on Google Exacycle reveal ligand modulation of GPCR activation pathways
19天前
已完结
Investigation of allosteric coupling in human β2-adrenergic receptor in the presence of intracellular loop 3
19天前
已完结
Structure-based discovery of nonopioid analgesics acting through the α 2A -adrenergic receptor
28天前
已完结
Ligand-specific conformational dynamics of the α2A-adrenergic receptor revealed by hydrogen-deuterium exchange mass spectrometry
28天前
已完结
Structural insights into ligand recognition, activation, and signaling of the α 2A adrenergic receptor
28天前
已完结
5-ht5A receptors as a therapeutic target
1个月前
已完结
SB-699551-A (3-cyclopentyl-N-[2-(dimethylamino)ethyl]-N-[(4′-{[(2-phenylethyl)amino]methyl}-4-biphenylyl)methyl]propanamide dihydrochloride), a novel 5-ht5A receptor-selective antagonist, enhances 5-HT neuronal function: Evidence for an autoreceptor role for the 5-ht5A receptor in guinea pig brain
1个月前
已完结
Medicinal Chemistry of 5-HT5A Receptor Ligands: A Receptor Subtype with Unique Therapeutical Potential
1个月前
已完结
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