Lv56
1080 积分 2024-07-02 加入
Development of Cathepsin B-Responsive GalNAc-PROTACs for Hepatocyte-Targeting Protein Degradation
1天前
已完结
Lessons learned in linking PROTACs from discovery to the clinic
2天前
已完结
The polypharmacology of psychedelics reveals multiple targets for potential therapeutics
4天前
已完结
Discovery of Atirmociclib (PF-07220060): A Potent and Selective CDK4 Inhibitor
4天前
已完结
Design and Optimization of LOXL2 and sGC Dual-Target Regulators Targeting Extracellular Matrix Dysregulation and Vasodilation for the Treatment of Pulmonary Arterial Hypertension
5天前
已完结
SINE compounds activate exportin 1 degradation through an allosteric mechanism
7天前
已完结
Degrader-Drug Conjugate (DDC) Mediated Immunochemotherapy for Tumor Treatment
7天前
已完结
Chromothripsis and ecDNA initiated by N4BP2 nuclease fragmentation of cytoplasm-exposed chromosomes
7天前
已完结
Positive allosteric mechanisms of adenosine A1 receptor-mediated analgesia
8天前
已完结
Intranasal administration of exosomes derived from adipose mesenchymal stem cells ameliorates depressive-like behaviors and inhibits inflammation via AMPK/mTOR-mediated autophagy
9天前
已完结