Lv5
980 积分 2024-09-04 加入
A positron emission tomography microdosing study with sertraline in healthy volunteers
13天前
已完结
Open label, three period, single sequence, study of 5, 25, 50 mg sertraline pharmacokinetics in healthy male Korean volunteers
15天前
已完结
Desipramine Pharmacokinetics When Coadministered With Paroxetine or Sertraline in Extensive Metabolizers
1个月前
已完结
Sertraline N-Demethylation Is Catalyzed by Multiple Isoforms of Human Cytochrome P-450 In Vitro
1个月前
已关闭
Pediatric off-label use and nonadherence management for nadolol: A mechanistic PBPK model incorporating ontogeny scaling from interracial adults to children
1个月前
已完结
Development and Validation of Physiologically Based Pharmacokinetic Model of Levetiracetam to Predict Exposure and Dose Optimization in Pediatrics
1个月前
已完结
Physiologically based pharmacokinetic modeling of tapentadol in children to support pediatric dose selection
1个月前
已完结
In Vitro and In Vivo Metabolism of a Novel Antimitochondrial Cancer Metabolism Agent, CPI-613, in Rat and Human
1个月前
已完结
Mass Balance of the Indoleamine 2,3-Dioxygenase Inhibitor Navoximod (GDC-0919) in Rats and Dogs: Unexpected Cyanide Release from Imidazo[5,1-a]isoindole and Species Differences in Glucuronidation
1个月前
已关闭
Metabolic Disposition of Osimertinib in Rats, Dogs, and Humans: Insights into a Drug Designed to Bind Covalently to a Cysteine Residue of Epidermal Growth Factor Receptor
1个月前
已完结