Lv31
290 积分 2025-07-07 加入
Radiotherapy activates picolinium prodrugs in tumours
25分钟前
待确认
Intramolecular hydrogen bond interruption and scaffold hopping of TMC-5 led to 2-(4-alkoxy-3-cyanophenyl)pyrimidine-4/5-carboxylic acids and 6-(4-alkoxy-3-cyanophenyl)-1,2-dihydro-3H-pyrazolo[3,4-d]pyrimidin-3-ones as potent pyrimidine-based xanthine oxidase inhibitors
18天前
已完结
Chalcone derivatives as xanthine oxidase inhibitors: synthesis, binding mode investigation, biological evaluation, and ADMET prediction
2个月前
已完结
Discovery of 1-Difluoromethyl-3-(3-cyanophenyl)-6-[4-(trifluoromethoxy)phenyl]imidazo[1,5-a]pyrazin-8-(7H)-one as a Potent P2Y1 Antagonist for the Treatment of Ischemic Stroke and Myocardial Infarction
3个月前
已完结
In Vivo Self‐Assembly of PROTACs by Bioorthogonal Chemistry for Precision Cancer Therapy
3个月前
已完结
The landscape of small-molecule prodrugs
3个月前
已完结
Immunogenic camptothesome nanovesicles comprising sphingomyelin-derived camptothecin bilayers for safe and synergistic cancer immunochemotherapy
3个月前
已完结
Competitive SPR Chaser Assay to Study Biomolecular Interactions with Very Slow Binding Dissociation Rate Constant
4个月前
已完结
The P2Y1Receptor as a Target for New Antithrombotic Drugs: A Review of the P2Y1Antagonist MRS‐2179
4个月前
已完结
One‐Pot Preparation of Unsymmetrical Biaryls via Suzuki Cross‐Coupling Reaction of Aryl Halide using Phase‐Transfer Catalyst in a Biphasic Solvent System
4个月前
已完结
In silico analysis identified potential interaction between glutathione and spliceosome in Nager Syndrome
4个月前
已采纳
In silico analysis identified potential interaction between glutathione and spliceosome in Nager Syndrome
4个月前
已采纳
In silico analysis identified potential interaction between glutathione and spliceosome in Nager Syndrome
4个月前
已采纳
Anti-inflammatory activity of Nectandra angustifolia (Laurel Amarillo) ethanolic extract
4个月前
已采纳
Mitochondrial Priming by CD28
4个月前
已采纳
SnapShot: Phosphoregulation of Mitosis
4个月前
已采纳
Apical clathrin-coated pits control the location, timing, and scale of microvillar growth
4个月前
已采纳
Mitochondrial E3 ubiquitin ligase 1 promotes brain injury by disturbing mitochondrial dynamics in a rat model of ischemic stroke
4个月前
已采纳
In vitro and in vivo anticancer activity of a novel puerarin nanosuspension against colon cancer, with high efficacy and low toxicity
4个月前
已采纳
Changes in physico-chemical properties and gel-forming ability of lizardfish (Saurida tumbil) during post-mortem storage in ice
4个月前
已采纳
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