Lv11
20 积分 2025-07-08 加入
Aficamten in the treatment of obstructive hypertrophic cardiomyopathy
13小时前
待确认
Organoids and organs-on-chips: Recent advances, applications in drug development, and regulatory challenges
10天前
已完结
In vitroandin vivopharmacokinetic characterization of mavacamten, a first-in-class small molecule allosteric modulator of beta cardiac myosin
15天前
已完结
In vitro and in vivo preclinical pharmacokinetic characterization of aficamten, a small molecule cardiac myosin inhibitor
16天前
已完结
In vitro and in vivo preclinical pharmacokinetic characterization of aficamten, a small molecule cardiac myosin inhibitor
22天前
已完结
Cryo-EM structures of cardiac muscle α-actin mutants M305L and A331P give insights into the structural mechanisms of hypertrophic cardiomyopathy
1个月前
已完结
Cryo-Electron Microscopy Reveals Cardiac Myosin Binding Protein-C M-Domain Interactions with the Thin Filament
1个月前
已完结
Understanding hypertrophic cardiomyopathy and its regulation by myosin drugs
1个月前
已完结
Structure–function relationship and physiological role of apelin and its G protein coupled receptor
1个月前
已完结
GPCR structure and function relationship: identification of a biased apelin receptor mutant
1个月前
已完结
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