Lv1
40 积分 2025-09-16 加入
Discovery and Characterization of Benzamide Derivatives as Highly Potent SUCNR1 Antagonists for Cancer Immunotherapy
6小时前
已完结
Dual Allosteric Targeting of SHP2: Development of Bivalent Inhibitors with Enhanced Potency for Cancer Treatment
6小时前
已完结
Toward targeting the untargetable: A non-canonical EGFR-peptide–drug conjugate achieves potent antitumor activity in KRAS-mutant CRC
6小时前
已关闭
Structure-Based Discovery of HS34: A Highly Selective and Orally Bioavailable CDK9 Inhibitor for Triple-Negative Breast Cancer
1个月前
已完结
Metal-Free Photocatalyst Photo-oxidizes NADPH to Trigger Pyropstosis and Disulfidptosis for Photocatalytic Therapy of Hypoxia Tumor
1个月前
已完结
Co-delivery of a STING agonist and indoleamine 2,3-dioxygenase 1 blockade activates type I dendritic cells in cancer
1个月前
已关闭
A Targeted Covalently Activated Chemotherapy Strategy Synergistically Enhances Cytotoxicity of Ibrutinib and Selectivity of Doxorubicin to B-cell Lymphoma Cells
2个月前
已完结
A Novel CSN5 Inhibitor Drives Tumor-Intrinsic PD-L1 Degradation and Exerts Direct Antitumor Efficacy in Triple-Negative Breast Cancer
2个月前
已关闭
Discovery of Oxime Ether Derivatives as Second-Generation PRMT5 Inhibitors for the Treatment of Triple Negative Breast Cancer
4个月前
已完结
A New Class of Multitargeting PtIV Anticancer Agents: Prodrugs That Release PtII Drugs and Bioactive Moieties Tethered to PtIV via a Tertiary Amine
4个月前
已关闭
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