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398 积分 2025-09-25 加入
The TREM2 agonistic antibody AL002 in early Alzheimer’s disease: a phase 2 randomized trial
2个月前
已完结
Trilobatin rescues cognitive impairment of Alzheimer’s disease by targeting HMGB1 through mediating SIRT3/SOD2 signaling pathway
2个月前
已完结
The TREM2 agonistic antibody AL002 in early Alzheimer’s disease: a phase 2 randomized trial
2个月前
已完结
Brain delivery of therapeutic proteins using an Fc fragment blood-brain barrier transport vehicle in mice and monkeys
4个月前
已完结
A TREM2 antibody energizes microglia
4个月前
已完结
Pharmacological and functional characterization of the first small molecule TREM2 agonist, VG‐3927, for the treatment of Alzheimer’s disease
4个月前
已完结
Rethinking TREM2 as a target for Alzheimer's disease after the INVOKE-2 trial failure
4个月前
已完结
INVOKE-2 - A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of AL002 in Participants with Early Alzheimer’s Disease (P17-3.005)
5个月前
已完结
Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
5个月前
已完结
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
5个月前
已完结
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