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278 积分 2025-09-25 加入
Rethinking TREM2 as a target for Alzheimer's disease after the INVOKE-2 trial failure
21小时前
待确认
INVOKE-2 - A Phase 2 Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of AL002 in Participants with Early Alzheimer’s Disease (P17-3.005)
12天前
已完结
Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
20天前
已完结
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
24天前
已完结
Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium
25天前
已完结
Inflammatory aspects of Alzheimer's disease
1个月前
已完结
Neuroinflammation and microglial activation in Alzheimer disease: where do we go from here?
1个月前
已完结
Neuroinflammation in Alzheimer disease
1个月前
已完结
A tetravalent TREM2 agonistic antibody reduced amyloid pathology in a mouse model of Alzheimer's disease
1个月前
已完结
Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer's disease
1个月前
已完结
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