Lv2
117 积分 2020-06-28 加入
Preclinical evaluation of a novel antibody–drug conjugate OBI-992 for Cancer therapy
10天前
已完结
Discovery and Characterization of (8S,9R)-5-Fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-2,7,8,9-tetrahydro-3H-pyrido[4,3,2-de]phthalazin-3-one (BMN 673, Talazoparib), a Novel, Highly Potent, and Orally Efficacious Poly(ADP-ribose) Polymerase-1/2 Inhibitor, as an Anticancer Agent
10天前
已完结
The Synergistic Effect of PARP Inhibitors and Irinotecan in Small Cell Lung Cancer Cells
10天前
已完结
Expanding the payload scope in antibody-drug conjugates by delivery of hydroxy-containing drugs through self-immolative phosphoramidates
14天前
已完结
Enzyme-Agnostic Lysosomal Screen Identifies New Legumain-Cleavable ADC Linkers
1个月前
已完结
Discovery of Potent and Selective Inhibitors of Ataxia Telangiectasia Mutated and Rad3 Related (ATR) Protein Kinase as Potential Anticancer Agents
1个月前
已完结
Targeting ATR in vivo using the novel inhibitor VE-822 results in selective sensitization of pancreatic tumors to radiation
1个月前
已完结
A Novel Dual-Payload ADC Platform Integrating Exatecan and Triptolide to Enhance Antitumor Efficacy and Overcome Resistance
1个月前
已完结
A comparison of the activity, lysosomal stability, and efficacy of legumain-cleavable and cathepsin-cleavable ADC linkers
1个月前
已完结
Enzyme-Agnostic Lysosomal Screen Identifies New Legumain-Cleavable ADC Linkers
1个月前
已完结