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238 积分 2025-07-30 加入
PROTACs Targeting BRM (SMARCA2) Afford Selective In Vivo Degradation over BRG1 (SMARCA4) and Are Active in BRG1 Mutant Xenograft Tumor Models
22天前
已完结
Direct Stereospecific Deoxyamination of Alcohols Enabled by Li-Mediated SuFEx
1个月前
已完结
Syntheses with heterocyclic ?-enaminonitriles: An expeditious synthetic approach to polyfunctionally substituted 5-phenylsulfonylthiophenes and their fused derivatives
1个月前
已完结
β-Ketosulfones in Gewald and Friedlaender chemistry. Design, synthesis, structure and in silico ADMET assessment of products
1个月前
已关闭
Synthesis and Biological Activity of a Novel Series of 6-Substituted Thieno[2,3-d]pyrimidine Antifolate Inhibitors of Purine Biosynthesis with Selectivity for High Affinity Folate Receptors over the Reduced Folate Carrier and Proton-Coupled Folate Transporter for Cellular Entry†
1个月前
已完结
Contemporary design of small-molecule kinase modulators: orthosteric, allosteric and induced-proximity strategies
5个月前
已完结
Shifts in pharma’s therapeutic area focus
5个月前
已完结
Biocatalytic cascades enable manufacture of the macrocyclic peptide enlicitide
5个月前
已完结
Process Development toward a Key Fragment of the PCSK9 Inhibitor Enlicitide Decanoate
5个月前
已完结
Total Synthesis of Enlicitide Decanoate
5个月前
已完结
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