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8 积分 2025-07-03 加入
Liver-targeted degradation of BRD4 reverses hepatic fibrosis and enhances metabolism in murine models
2个月前
已完结
Liver-targeted degradation of BRD4 reverses hepatic fibrosis and enhances metabolism in murine models
2个月前
已完结
Development of Cathepsin B-Responsive GalNAc-PROTACs for Hepatocyte-Targeting Protein Degradation
2个月前
已完结
DGAT2: A Key Therapeutic Target in Lipid Synthesis Regulation and Metabolic Diseases
2个月前
已完结
Inflammation promotes hepatic but not adipose tissue DGAT2 expression and triglyceride synthesis in MAFLD mice
2个月前
已完结
IL-32 is a stress-responsive node locked in a noncanonical NF-κB inflammatory loop during MASLD to HCC transition
2个月前
已完结
Targeting PYK2 with heterobifunctional T6BP helps mitigate MASLD and MASH-HCC progression
2个月前
已完结
Rational design and discovery of potent PROTAC degraders of ASK1: a targeted therapy in MASH
2个月前
已完结
Efficacy and safety of ervogastat alone and in combination with clesacostat in patients with biopsy-confirmed metabolic dysfunction-associated steatohepatitis and F2–F3 fibrosis (MIRNA): results from a phase 2, randomised, double-blind, double-dummy study
2个月前
已完结
DGAT2: A Key Therapeutic Target in Lipid Synthesis Regulation and Metabolic Diseases
2个月前
已完结
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